<p>Cancers of the immune system (lymphomas) are extremely sensitive to radiation. Medical research over the last decade has lead to the development of monoclonal antibodies that can target lymphoma cells being attached to radioactive isotopes that help destroy those cells. Such treatment is known as radioimmunotherapy and this article describes its use for non-Hodgkin’s lymphoma. Nurses need to become familiar with how radioimmunotherapy differs from conventional chemotherapy.</p>