Safeguarding vulnerable adults and children is a legal requirement and is essential in nursing and healthcare practice. This article describes the development and establishment of a structured approach to safeguarding education and student support in one pre-registration nursing programme in the UK. This approach involved the development of an academic safeguarding lead role, extensive curriculum development, and implementation of policies and procedures for raising and escalating concerns. The authors suggest that this integrative and comprehensive model should be used in all higher education institutions providing nurse education.