Nebulisation is an important and common method of administering medication to patients with respiratory disease. Although the routine use of nebulisers is contentious, they are helpful when the patient is unable to use other devices, perhaps because of illness or poor dexterity, and are recommended in certain clinical situations, such as acute, life-threatening asthma. This article aims to inform nurses of current evidence regarding the advantages and limitations of nebuliser therapy. Patient experiences of receiving nebulisers are discussed, as well as the importance of cleaning and maintaining the equipment.