The drug naloxone reverses opioid overdose, potentially saving the lives of people who use nitazenes, the widely available group of synthetic drugs 500 times more potent than heroin. Nitazene-related deaths have risen sharply in the UK. Undergraduate nursing students at University of Bradford are believed to be the first in the UK to learn how to administer naloxone. They are also educated in how drug use is changing as the supply of heroin declines and the availability of nitazenes expands, and about addressing stigma in relation to drug use. Experts offer nursing students advice on how to improve care of people using drugs and a nursing student describes his experience of learning how to administer naloxone.