Why you should read this article

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To enhance your knowledge of the pathophysiology, transmission and treatment of Clostridioides difficile infection, and to be aware of its growing community expression

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To update your knowledge and ensure your practice is based on the latest evidence regarding the measures for preventing C. difficile cross-infection

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To enhance your knowledge of patient education regarding C. difficile infection in community settings

Clostridioides difficile infection is increasing in expression in hospital and community settings, making it a significant public health issue. It is essential to reinforce knowledge of the disease, including its symptoms, diagnosis, treatment and effective prevention and control measures, to reduce the risk that this disease represents for patients. This article outlines the established risk factors for C. difficile infection, relevant aspects of its epidemiology, diagnostic testing, treatment and preventive measures.