There is an increased prevalence of dementia in people with a learning disability, but modifiable lifestyle factors, such as healthy eating, may reduce this risk. This article reviews the evidence on fatty acids, B vitamins, and antioxidants, that have been indicated as preventive measures in neurodegeneration. It also highlights the evidence suggesting that encouraging a healthy and varied diet early in life, and sustaining this through adulthood and later in life, promotes neurological health in people with a learning disability.