Background Clinical nurse specialists (CNSs) work in advanced practice and aim to enhance patients’ experiences through expert consultation and providing evidence-based nursing care. They also have a role in educating colleagues about new research and practice innovations.

Aim To understand the perceptions of nurse leaders and staff nurses regarding the effect of the CNS role on quality improvement and to identify the unique features of the CNS role that can drive change within an organisation.

Method This qualitative study used interviews with nurse leaders and staff nurses in the US to explore their perceptions of the CNS role. It was hoped that understanding these perceptions would enable nurse leaders to realise the full potential of the CNS role in developing meaningful professional relationships and shaping organisational culture.

Findings A total of 24 participants completed the interviews. Five themes were extrapolated from the interview data: a hospital and unit with cultural rules of quality and evidence-based practice; interdependence among roles; diversity and innovation; attributes; and associative capacity.

Conclusion The CNS role is essential, providing clinical and financial value to healthcare organisations through the professional development of novice nurses, the enhancement of practice environments and improved patient outcomes.